Dr. X's cutting-edge new technique in surgery? Stem cells combined with 3D printing to regenerate human organs

Fans of Japanese dramas must have seen the dispatch female doctor Michiko Daimon ( Doctor X Surgeon Michiko Daimon ), a lonely female doctor known as Dr. X, with extraordinary surgical skills, but she despises entering the white tower, choosing to be a freelancer. Her classic catchphrase is '私、失敗しないので ( I will not fail ).' Michiko Daimon, who usually keeps to herself, has almost no friends, except for her agent, Jing, who helps her with cases and often plays mahjong together. Her interests and expertise lie in surgery. This unique and independent surgeon is portrayed by Ryoko Yonekura and has become a representative work in her acting career. Surprisingly, this drama has been running for twelve years, showcasing the latest medical technologies used in surgeries, whether in the drama version or the currently popular movie version.

Movie Introduction for Doctor X Final Theatrical Edition

The dispatch of female doctor Daimon Unknownko began broadcasting on TV Asahi in Japan in 2012, starring Ryoko Yonekura as Daimon Unknown, who has superb surgical skills, and the opening scene of each episode will see her dressed up and stepping on three-inch heels and making an imposing appearance. The gate takes on all kinds of impossible surgical tasks, and it will definitely not fail, and it will definitely go to the public bath after the successful operation, drink countless cups of saccharin, and Uncle Jing, the agent and partner, will take the cantaloupe and the bill to the dean of the Eastern Emperor University to pay an amazing surgical fee.

After twelve years, the Japanese drama 'Dispatch Female Doctor' has aired seven seasons. As all the doctors in the drama are facing a midlife crisis, becoming the 'oji-san' and 'oba-san' they never wanted to be, this classic Japanese drama is likely coming to an end, with no more production in the future. Fortunately, a theatrical version has been released, allowing Dr. X to appear on the big screen of the cinema, giving viewers a chance to relive all the content at once and experience a very shocking ending. The final theatrical version contains all the classic scenes, as well as more dramatic tension. The ending twists and turns, handling well the human conflicts and contradictions arising from the medical system and ethical morals. It also reveals the mysterious background of Dr. X and the relationship with Uncle Shoujing. It is highly recommended to watch in theaters. After this movie is released, it may be the last time we see Dr. X in action (tears).

Innovative medical technology is tough: Are stem cells and 3D printed artificial blood vessels in movies real?

In the movie 'Dispatch Female Doctor X,' Mamoru Daimon used 3D printed blood vessels and artificial hearts during surgery. Is it possible to achieve this in the real world? According to the latest medical reports, the United States has conducted research and experiments. In the future, it may be possible to create artificial vascular organs by combining stem cells and 3D printing technology and transplant them into the human body.

Living tissue bioprinting technology may soon be realized, Professor Guohao Dai of Northeastern University recently applied for a patent for their 3D printed soft tissue's elastic hydrogel material. In modern medicine, 3D printing technology has been used to manufacture hard implants such as skull plates and hip joints, prosthetic limbs, and medical devices. However, the printing technology for organs and blood vessels has always been in the research stage. The latest development is the new hydrogel material that can be used for cell culture and can be combined with 3D printing to create blood vessels and organs.

Professor Dai's research focuses on 3D bioprinting, stem cell and vascular bioengineering. He says that 3D printing of organs and soft tissues still has great challenges, and he focuses his research on new materials for 3D bioprinting.

Current 3D printers use polymers, plastic filaments, powders, or resins to print objects, which harden upon cooling. Soft tissues require elastic materials that can stretch and shrink, a technology that is currently lacking. Elasticity is crucial for maintaining normal tissue function.

The developed hydrogels are a kind of synthetic polymer that can retain moisture, and can be used in masks containing skin nutrients, wound dressings for drug delivery, and soft contact lenses containing a large amount of water to provide comfort and oxygen transport. However, traditional hydrogels are too fragile for 3D printing, unable to withstand stretching or twisting, limiting medical applications.

To solve this problem, Guohao Dai teamed up with Yi Hong of the University of Texas at Arlington to find ways to make the hydrogel elastic, and the professor used his expertise in 3D printing to modify the properties of the hydrogel so that it could pass through the printer's print nozzle.

This new material can dissolve in liquid solution, and after printing, it can encapsulate a large amount of water, simulating an environment where the average human body is sixty percent water. Before printing, cells are injected into the liquid solution. After printing, the object will be exposed to blue light, triggering a photochemical reaction, giving the gel elasticity without damaging the living cells. It can also be printed into any geometric shape, and then the cells can reproduce and grow within the printed structure, even simulating human blood pressure under pulsatile pressure.

Another feature of the new elastic hydrogel is its biodegradability (degradation), as it is an exogenous polymer, it must ultimately be completely decomposed, allowing the cells to replace the gel with their own collagen and elastin, forming strong natural blood vessels.

The ultimate goal of this technology is to allow patients to extract their own cells to create blood vessels for themselves, and as the hydrogel degrades, the body will naturally replace them, forming fully functional tissues or organs. This kind of regenerative medicine technology is still new research, but in the movie, the screenwriters can't wait to make it happen first.

This article dispatches the female doctor Dr. X to perform tough new surgical techniques? The combination of stem cells and 3D printing regenerates human organs first appeared in Chain News ABMedia.