This comprehensive guide compares NANO and UNI, two distinct cryptocurrency assets serving different market roles. NANO, launched in 2018, focuses on peer-to-peer payment infrastructure with zero-fee transactions and fixed supply mechanisms. UNI, introduced in 2020, functions as the governance token for Uniswap's decentralized exchange protocol. The analysis examines historical price trends, tokenomics differences, institutional adoption, and technical ecosystems, revealing that UNI dominates in market capitalization ($3.40B vs $98.54M) and trading volume ($1.32M vs $12K daily), while NANO presents alternative payment network exposure. Through detailed price forecasts spanning 2026-2031, investment strategies tailored to different investor profiles, and risk comparisons across market, technical, and regulatory dimensions, this article provides actionable insights to determine which asset aligns better with your investment objectives and risk tolerance in evolving cryptocurrency markets.